blast crisis

blast crisis
A phase of chronic myelogenous leukemia in which tiredness, fever, and an enlarged spleen occur during the blastic phase, when more than 30% of the cells in the blood or bone marrow are blast cells (immature blood cells).

English dictionary of cancer terms . 2015.

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  • blast crisis — n the terminal stage of chronic myelogenous leukemia that is characterized by a marked increase in the proportion of blast cells, by fever and pain in the bones, and by increased severity of anemia, thrombocytopenia, and splenomegaly called also… …   Medical dictionary

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  • Blast phase — Refers to advanced chronic myelogenous leukemia. In this phase, the number of immature, abnormal white blood cells in the bone marrow and blood is extremely high. Also called blast crisis …   Medical dictionary

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  • crisis — 1. A sudden change, usually for the better, in the course of an acute disease, in contrast to the gradual improvement by lysis. 2. A paroxysmal pain in an organ or circumscribed region of the body occurring in the course of …   Medical dictionary

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  • blastic crisis — blas·tic crisis blas tik n blast crisis …   Medical dictionary

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