- bispecific monoclonal antibody
- A monoclonal antibody that binds two different types of antigen. Bispecific monoclonal antibodies do not occur naturally; they must be made in the laboratory.
English dictionary of cancer terms . 2015.
bispecific monoclonal antibody
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Bispecific monoclonal antibody — A bispecific monoclonal antibody is a monoclonal antibody that binds two different types of antigen. Bispecific monoclonal antibodies do not occur naturally; they must be made in the laboratory. External links *… … Wikipedia
Monoclonal antibody therapy — Each antibody binds only one specific antigen. Monoclonal antibody therapy is the use of monoclonal antibodies (or mAb) to specifically bind to target cells or proteins. This may then stimulate the patient s immune system to attack those cells.… … Wikipedia
Monoclonal antibodies — A general representation of the methods used to produce monoclonal antibodies. Monoclonal antibodies (mAb or moAb) are monospecific antibodies that are the same because they are made by identical immune cells that are all clones of a unique… … Wikipedia
Bispecific antibody — A bispecific antibody is a monoclonal antibodies which is designed to bind to two different antigens.One benefit of this approach is that it is possible for such an antibody to simultaneously bind to a cytotoxic cell (using a receptor like CD3)… … Wikipedia
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Bispezifischer Antikörper — Ein bispezifischer Antikörper (Abkürzung: BsMAb von engl. bispecific monoclonal antibody), auch als Hybrid Antikörper bezeichnet, ist ein Immunkonjugat, das aus Bestandteilen von zwei unterschiedlichen monoklonalen Antikörpern aufgebaut sind.… … Deutsch Wikipedia
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Chemically linked Fab — Example of chemically linked Fabs: two Fab fragments linked with a thioether, resulting in a F(ab )2. The molecule is bound to a tumour cell via the tumour antigen CD30 and to a macrophage via an Fc receptor. Two chemically linked fragments… … Wikipedia
Single-chain variable fragment — Rotating scFv fragment with highlighted complementary determining regions (CDRs) … Wikipedia
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