Zarnestra

Zarnestra
A substance that is being studied in the treatment of acute myeloid leukemia (AML) and other types of cancer. It belongs to the family of drugs called farnesyltransferase inhibitors. Also called tipifarnib and R115777.

English dictionary of cancer terms . 2015.

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  • Farnesyltransferase inhibitor — The farnesyltransferase inhibitors (FTIs) are a class of experimental cancer drugs that target protein farnesyltransferase with the downstream effect of preventing the proper functioning of the Ras (protein), which is commonly abnormally active… …   Wikipedia

  • Tipifarnib — Drugbox IUPAC name = 6 [amino (4 chlorophenyl) (3 methylimidazol 4 yl)methyl] 4 (3 chlorophenyl) 1 methylquinolin 2 one CAS number = CAS supplemental = ATC prefix = ATC suffix = ATC supplemental = PubChem = 148193 DrugBank = chemical formula =… …   Wikipedia

  • R115777 — A substance that is being studied in the treatment of acute myeloid leukemia (AML) and other types of cancer. It belongs to the family of drugs called farnesyltransferase inhibitors. Also called tipifarnib and Zarnestra …   English dictionary of cancer terms

  • tipifarnib — A substance that is being studied in the treatment of acute myeloid leukemia (AML) and other types of cancer. It belongs to the family of drugs called farnesyltransferase inhibitors. Also called R115777 and Zarnestra …   English dictionary of cancer terms

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