tumor-specific antigen

tumor-specific antigen
A protein or other molecule that is unique to cancer cells or is much more abundant in them. These molecules are usually found in the plasma (outer) membrane, and they are thought to be potential targets for immunotherapy or other types of anticancer treatment.

English dictionary of cancer terms . 2015.

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  • tumor-specific antigen — (TSA) any cell surface antigen of a tumor that does not occur on normal cells of the same origin …   Medical dictionary

  • tumor-associated antigen — (TAA) an antigen that is associated with tumor cells; it may also be found under other conditions, as on normal cells during fetal life (oncofetal antigen) or on normal adult cells specific to certain organs (organ specific antigen), or may occur …   Medical dictionary

  • tumor rejection antigen — (TRA) tumor specific transplantation a …   Medical dictionary

  • Prostate specific antigen — (PSA) is a protein produced by the cells of the prostate gland. PSA is present in small quantities in the serum of normal men, and is often elevated in the presence of prostate cancer and in other prostate disorders. A blood test to measure PSA… …   Wikipedia

  • tumor-specific transplantation antigen — (TSTA) any of the cell surface histocompatibility antigens of a given tumor that evoke a specific immune response on transplantation to a syngeneic host …   Medical dictionary

  • Tumor antigen — is a substance produced in tumor cells that triggers an immune response in the host. Tumor antigens are useful in identifying tumor cells and are potential candidates for use in cancer therapy. Mechanism of tumor antigenesisNormal proteins in the …   Wikipedia

  • Test, prostate specific antigen — A test used to screen for cancer of the prostate and to monitor treatment. PSA is a protein produced by the prostate gland. Although most PSA is carried out of the body in semen, a very small amount escapes into the blood stream. The PSA test is… …   Medical dictionary

  • Antigen — Each antibody binds to a specific antigen; an interaction similar to a lock and key. An antigen is a foreign molecule that, when introduced into the body, triggers the production of an antibody by the immune system. The immune system will then… …   Wikipedia

  • Tumor marker — A tumor marker is a substance found in the blood, urine, or body tissues that can be elevated in cancer, among other tissue types. There are many different tumor markers, each indicative of a particular disease process, and they are used in… …   Wikipedia

  • antigen — Any substance that, as a result of coming in contact with appropriate cells, induces a state of sensitivity and/or immune responsiveness after a latent period (days to weeks) and that reacts in a demonstrable way with antibodies and/or immune… …   Medical dictionary

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