tumor vasculature–targeted tumor necrosis factor alpha

tumor vasculature–targeted tumor necrosis factor alpha
A substance that is being studied in the treatment of cancer. It is made by linking tumor necrosis factor (TNF) to a peptide. The peptide binds to tumor blood vessels and TNF damages them. It belongs to the family of drugs called biological response modifiers. Also called NGR-TNF.

English dictionary of cancer terms . 2015.

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  • NGR-TNF — A substance being studied in the treatment of cancer. It is made by linking tumor necrosis factor (TNF) to a peptide. The peptide binds to tumor blood vessels, and TNF damages them. It is a type of biological response modifier. Also called tumor… …   English dictionary of cancer terms

  • Survivin — Survivin, also called Baculoviral IAP repeat containing 5 (BIRC5), is a human gene that is part of the inhibitor of apoptosis family (IAP). The survivin protein functions to inhibit caspase activation therefore leading to negative regulation of… …   Wikipedia

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