ribonucleotide reductase inhibitor

ribonucleotide reductase inhibitor
A family of anticancer drugs that interfere with the growth of tumor cells by blocking the formation of deoxyribonucleotides (building blocks of DNA).

English dictionary of cancer terms . 2015.

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  • Ribonucleotide reductase — protein Name = ribonucleotide reductase M1 polypeptide caption = width = HGNCid = 10451 Symbol = RRM1 AltSymbols = EntrezGene = 6240 OMIM = 180410 RefSeq = NM 001033 UniProt = P23921 PDB = ECnumber = 1.17.4.1 Chromosome = 11 Arm = p Band = 15.5… …   Wikipedia

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  • Dihydrofolate reductase — Ribbon diagram of human dihydrofolate reductase in complex with folate (blue). From PDB 1DRF …   Wikipedia

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  • Dihydropteroate synthase inhibitor — A dihydropteroate synthetase inhibitor is a drug that inhibits the action of dihydropteroate synthetase. Most are sulfonamides. Tetrahydrofolate synthesis pathway In bacteria, antibacterial sulfonamides act as competitive inhibitors of the enzyme …   Wikipedia

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