psoralen

psoralen
A substance from plants that is sensitive to light (or can be activated by light). Psoralens are used together with UV light to treat psoriasis, vitiligo, and skin nodules of cutaneous T-cell lymphoma. They are also being studied in the treatment of graft-versus-host disease. They belong to the family of drugs called furocoumarins. An example of a psoralen is methoxsalen.

English dictionary of cancer terms . 2015.

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  • psoralen — [sôr′ə lən] n. any of various derivatives of coumarin used in drugs to treat psoriasis, etc.: when activated by sunlight it causes the skin to darken …   English World dictionary

  • Psoralen — Chembox new Name = Psoralen IUPACName = 7H furo [3,2 g] chromen 7 one or 7H furo [3,2 g] benzopyran 7 one ImageFile = Psoralen.png ImageName = Chemical structure of psoralen Section1 = Chembox Identifiers CASNo = 66 97 7 SMILES = O=C1OC2=CC3=C (C …   Wikipedia

  • Psoralen — Strukturformel Allgemeines Name Psoralen Andere Namen 7H …   Deutsch Wikipedia

  • psoralen — noun Etymology: New Latin Psoralea, genus of plants from which it is isolated + English en, alteration of ene Date: 1933 a substance C11H6O3 found in some plants that photosensitizes mammalian skin and is used in conjunction with ultraviolet… …   New Collegiate Dictionary

  • psoralen — A phototoxic drug used by topical or oral administration for the treatment of vitiligo and psoriasis. Also present in oil of bergamot perfume and in fruits and vegetables such as limes, which may cause photosensitization. SEE ALSO …   Medical dictionary

  • psoralen — psoralenas statusas T sritis chemija formulė (=O)C₁₁H₆O₂ atitikmenys: angl. psoralen rus. псорален ryšiai: sinonimas – furo[3,2 g]benzpiran 7 onas …   Chemijos terminų aiškinamasis žodynas

  • psoralen — ˈsōrələ̇n, ˈsȯr noun ( s) Etymology: modification of New Latin Psoralea psoralea : a substance C11H6O3 found in some plants that photosensitizes mammalian skin and is used in conjunction with ultraviolet light to treat psoriasis ; also : any of… …   Useful english dictionary

  • Psoralen synthase — In enzymology, a psoralen synthase (EC number|1.14.13.102) is an enzyme that catalyzes the chemical reaction:(+) marmesin + NADPH + H+ + O2 ightleftharpoons psoralen + NADP+ + acetone + 2 H2OThe 4 substrates of this enzyme are (+) marmesin, NADPH …   Wikipedia

  • Psoralen photochemotherapy — A type of therapy in which the patient is exposed first to psoralens (drugs containing chemicals that react with ultraviolet light to cause darkening of the skin) and then to ultraviolet A (UVA light). Psoralen photochemotherapy is also called… …   Medical dictionary

  • psoralen and ultraviolet A therapy — PUVA therapy. A type of photodynamic therapy used to treat skin conditions such as psoriasis, vitiligo, and skin nodules of cutaneous T cell lymphoma. The patient receives psoralen (a drug that becomes active when it is exposed to light) by mouth …   English dictionary of cancer terms

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