panitumumab

panitumumab
A human monoclonal antibody that is being used to treat colorectal cancer that has spread to other parts of the body. It is used in patients whose disease has not gotten better during or after treatment with other anticancer drugs. It is also being studied in the treatment of other types of cancer. Monoclonal antibodies are made in the laboratory and can locate and bind to cancer cells. Panitumumab binds to the epidermal growth factor receptor (EGFR) and may block tumor cell growth. Also called ABX-EGF and Vectibix.

English dictionary of cancer terms . 2015.

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  • Panitumumab — Masse/Länge Primärstruktur 144,3 kDa …   Deutsch Wikipedia

  • Panitumumab — drugbox mab source = Human recombinant target = EGFR CAS number = 339177 26 3 ATC prefix = L01 ATC suffix = XC08 PubChem = DrugBank = C=6306 | H=9732 | N=1672 | O=1994 | S=46 molecular mass= 147 kDa bioavailability = protein bound = metabolism =… …   Wikipedia

  • panitumumab — noun A human monoclonal antibody used in the treatment of some cancers …   Wiktionary

  • panitumumab — pani·tu·mu·mab (pan″ĭ tooґmə mab) an antagonist of epidermal growth factor receptors, used in treatment of metastatic colorectal carcinoma; administered by intravenous infusion …   Medical dictionary

  • Vectibix — Panitumumab Größe 144,3 kDa Bezeichner Externe IDs CAS …   Deutsch Wikipedia

  • Cetuximab — ? Monoclonal antibody Type Whole antibody Source Chimeric (mouse/human) Target EGF receptor Clinical data AHFS/Drugs.com …   Wikipedia

  • Colorectal cancer — Classification and external resources Diagram of the lower gastrointestinal tract ICD 10 C …   Wikipedia

  • Monoclonal antibodies — A general representation of the methods used to produce monoclonal antibodies. Monoclonal antibodies (mAb or moAb) are monospecific antibodies that are the same because they are made by identical immune cells that are all clones of a unique… …   Wikipedia

  • Gemtuzumab ozogamicin — ? Monoclonal antibody Type Whole antibody Source Humanized (from mouse) Target CD33 Clinical data Trade names Mylotarg AHFS/ …   Wikipedia

  • Monoclonal antibody therapy — Each antibody binds only one specific antigen. Monoclonal antibody therapy is the use of monoclonal antibodies (or mAb) to specifically bind to target cells or proteins. This may then stimulate the patient s immune system to attack those cells.… …   Wikipedia

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