antimetabolite

antimetabolite
A drug that is very similar to natural chemicals in a normal biochemical reaction in cells but different enough to interfere with the normal division and functions of cells.

English dictionary of cancer terms . 2015.

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  • antimétabolite — ● antimétabolite nom masculin Chimiothérapie anticancéreuse. ⇒ANTIMÉTABOLITE, subst. masc. MÉD. ,,Substance entravant le métabolisme. En particulier, médicament (...) s opposant à certaines réactions chimiques intracellulaires et par conséquent à …   Encyclopédie Universelle

  • Antimetabolite — sind chemische Verbindungen, die natürlichen Metaboliten in ihrer chemischen Struktur ähneln, aber dessen Stoffwechselweg hemmen (Inhibitor). Ergebnis ist eine Störung der normalen Enzymfunktion in einem Stoffwechselweg oder biologischen Prozess …   Deutsch Wikipedia

  • antimetabolite — [an΄tī mə tab′ə līt΄; an΄tēmə tab′ə līt΄, an΄timə tab′ə līt΄] n. a drug or biochemical that inhibits a metabolic process by competing with a similarly shaped metabolite for a particular enzyme …   English World dictionary

  • antimetabolite — /an tee meuh tab euh luyt , an tuy /, n. 1. Biochem. any substance that interferes with growth of an organism by competing with or substituting for an essential nutrient in an enzymatic process. adj. 2. Pharm. of or pertaining to certain… …   Universalium

  • Antimetabolite — The drug methotrexate (right) is an antimetabolite that interferes with the metabolism of folic acid (left). An antimetabolite is a chemical that inhibits the use of a metabolite, which is another chemical that is part of normal metabolism.[1] …   Wikipedia

  • Antimétabolite — Un antimétabolite est une substance chimique qui empêche l utilisation d un métabolite, qui est un autre produit chimique qui fait partie du métabolisme normal. Ces substances sont souvent similaires dans leur structure à celle du métabolite avec …   Wikipédia en Français

  • antimetabolite — antimetabolitas statusas T sritis chemija apibrėžtis Biologiškai aktyvus junginys, inhibuojantis metabolizmo fermentus. atitikmenys: angl. antimetabolite rus. антиметаболит …   Chemijos terminų aiškinamasis žodynas

  • antimetabolite — antimetabolitas statusas T sritis ekologija ir aplinkotyra apibrėžtis Gamtinis ar sintetinis biologiškai aktyvus junginys (pvz., metatreksatas, merkaptopurinas, gemcitabinas), pakeičiantis metabolitus biocheminėse reakcijose, trikdantis medžiagų… …   Ekologijos terminų aiškinamasis žodynas

  • antimetabolite — noun Date: 1945 a substance that replaces or inhibits an organism s utilization of a metabolite …   New Collegiate Dictionary

  • antimetabolite — n. [Gr. anti, against; metabole, change] Any compound that interferes with normal cellular metabolism …   Dictionary of invertebrate zoology

  • antimetabolite — (an tī mē tab o laīt) A compound that blocks metabolic pathway function by competitively inhibiting a key enzyme s use of a metabolite because it closely resembles the normal enzyme substrate …   Dictionary of microbiology

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