monoclonal protein

monoclonal protein
An antibody or part of an antibody found in unusually large amounts in the blood or urine of people with multiple myeloma and other types of plasma cell tumors. Also called M protein.

English dictionary of cancer terms . 2015.

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  • Monoclonal gammopathy of undetermined significance — Classification and external resources Schematic representation of a normal protein electrophoresis gel. A small spike would be present in the gamma (γ) band in MGUS ICD 1 …   Wikipedia

  • Protein A/G — is a recombinant fusion protein that combines IgG binding domains of both Protein A and Protein G. Protein A/G contains four Fc binding domains from Protein A and two from Protein G, yielding a final mass of 50,460 daltons. The binding of Protein …   Wikipedia

  • Protein L — is a 36,000 dalton immunoglobulin binding protein isolated from the bacteria Peptostreptococcus magnus . Unlike Protein A and Protein G, which bind to the Fc region of immunoglobilins (antibodies), Protein L binds antibodies through light chain… …   Wikipedia

  • monoclonal gammopathy — n any of various disorders marked by proliferation of a single clone of antibody producing lymphoid cells resulting in an abnormal increase of a monoclonal antibody in the blood serum and urine and that include both benign or asymptomatic… …   Medical dictionary

  • Monoclonal antibodies — A general representation of the methods used to produce monoclonal antibodies. Monoclonal antibodies (mAb or moAb) are monospecific antibodies that are the same because they are made by identical immune cells that are all clones of a unique… …   Wikipedia

  • Monoclonal antibody therapy — Each antibody binds only one specific antigen. Monoclonal antibody therapy is the use of monoclonal antibodies (or mAb) to specifically bind to target cells or proteins. This may then stimulate the patient s immune system to attack those cells.… …   Wikipedia

  • Protein — A large molecule composed of one or more chains of amino acids in a specific order determined by the base sequence of nucleotides in the DNA coding for the protein. Proteins are required for the structure, function, and regulation of the body s… …   Medical dictionary

  • Monoclonal — Pertaining to a single clone of cells, a single cell and the progeny of that cell. As opposed to polyclonal. A monoclonal tumor is one that is derived from a single cell and the progeny of that cell. Monoclonal antibodies are produced by a single …   Medical dictionary

  • Monoclonal antibody — An antibody produced by a single clone of cells (specifically, a single clone of hybridoma cells) and therefore a single pure homogeneous type of antibody. Monoclonal antibodies can be made in large amounts in the laboratory and are a cornerstone …   Medical dictionary

  • Protein microarray — A protein microarray, sometimes referred to as a protein binding microarray, is a piece of glass on which different molecules of protein have been affixed at separate locations in an ordered manner thus forming a microscopic array. These are used …   Wikipedia

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