maximum tolerated dose

maximum tolerated dose
The highest dose of a drug or treatment that does not cause unacceptable side effects. The maximum tolerated dose is determined in clinical trials by testing increasing doses on different groups of people until the highest dose with acceptable side effects is found. Also called MTD.

English dictionary of cancer terms . 2015.

Игры ⚽ Нужен реферат?

Look at other dictionaries:

  • Maximum tolerated dose — For dietary recommendation, see Tolerable upper intake levels. Maximum tolerated dose (MTD) refers to the highest dose of a radiological or pharmacological treatment that will produce the desired effect without unacceptable toxicity [1]. The… …   Wikipedia

  • maximum tolerated dose — (MTD) tolerance d …   Medical dictionary

  • Dose — means quantity in the following fields: In nutrition, medicine, and toxicology: Dose (biochemistry), the quantity of something that may be eaten by or administered to an organism, or that an organism may be exposed to Medicine and toxicology… …   Wikipedia

  • dose — 1. The quantity of a drug or other remedy to be taken or applied all at one time or in fractional amounts within a given period. Cf.:dosage (2). 2. In nuclear medicine, amount of energy absorbed per unit mass of irradiated material (absorbed d.) …   Medical dictionary

  • tolerance dose — the largest quantity of an agent that can be administered without harm. Called also maximum tolerated d …   Medical dictionary

  • MTD — maximum tolerated dose; mean total dose; metastatic trophoblastic disease; Midwife Teacher s Diploma; minimal topological difference; Monroe tidal drainage; maximum tolerated dose; multidrug therapy; multiple tic disorder; Mycobacterium… …   Medical dictionary

  • MTD — • maximum tolerated dose; • mean total dose; • metastatic trophoblastic disease; • Midwife Teacher s Diploma; • minimal topological difference; • Monroe tidal drainage; • maximum tolerated dose; • multidrug therapy; • multiple tic disorder; •… …   Dictionary of medical acronyms & abbreviations

  • MTD — Maximum Tolerated Dose (Medical » Physiology) **** Memory Technology Devices (Business » Firms) * Mettler Toledo International, Inc. (Business » NYSE Symbols) * Month To Date (Business » Accounting) * Michael Tobias Design (Business » Firms) *… …   Abbreviations dictionary

  • Glossary of clinical trials — A glossary of terms used in clinical trials. NOTOC CompactTOC8 side = yes refs = yes A * Activities of daily living:: The tasks of everyday life. These activities include eating, dressing, getting into or out of a bed or chair, taking a bath or… …   Wikipedia

  • Ketamine — drugbox IUPAC name = 2 (2 chlorophenyl) 2 methylamino cyclohexan 1 one width = 150 CAS number = 6740 88 1 ATC prefix = N01 ATC suffix = AX03 ATC supplemental = ATC|N01|AX14 PubChem = 3821 DrugBank = APRD00493 C=13 | H=16 | Cl=1 | N=1 | O=1 smiles …   Wikipedia

Share the article and excerpts

Direct link
Do a right-click on the link above
and select “Copy Link”