intercalator

intercalator
In biochemistry, a type of molecule that binds to DNA and inserts itself into the DNA structure. Some intercalators are used as treatments for cancer.

English dictionary of cancer terms . 2015.

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  • intercalator — noun a) That which intercalates b) Any of several classes of small molecule that inserts itself into the structure of DNA See Also: intercalation …   Wiktionary

  • Intercalation (chemistry) — Intercalation induces structural distortions. Left: unchanged DNA strand. Right: DNA strand intercalated at three locations (red areas). In chemistry, intercalation is the reversible inclusion of a molecule (or group) between two other molecules… …   Wikipedia

  • DNA — For a non technical introduction to the topic, see Introduction to genetics. For other uses, see DNA (disambiguation). The structure of the DNA double helix. The atoms in the structure are colour coded by element and the detailed structure of two …   Wikipedia

  • Two-dimensional gel electrophoresis — Two dimensional gel electrophoresis, abbreviated as 2 DE or 2 D electrophoresis, is a form of gel electrophoresis commonly used to analyze proteins. Mixtures of proteins are separated by two properties in two dimensions on 2D gels.Basis for… …   Wikipedia

  • List of oncology-related terms — This is a list of terms related to oncology. The original source for this list was the U.S. National Cancer Institute s public domain Dictionary of Cancer Terms . NOTOC 1 * 10 propargyl 10 deazaaminopterin * 12 O tetradecanoylphorbol 13 acetate * …   Wikipedia

  • 7-Aminoactinomycin — (7 ADD) is a fluorescent DNA intercalator marketed by several companies including AnaSpec, Invitrogen, and Biotium. It binds double stranded DNA and can be excited by an argon ion laser to emit light at 647 nm wavelength. It binds GC regions… …   Wikipedia

  • Brostallicin — is a substance being studied in the treatment of cancer. It is a type of DNA intercalator. External links * [http://www.cancer.gov/Templates/db alpha.aspx?CdrID=269413 Brostallicin] entry in the public domain NCI Dictionary of Cancer Terms …   Wikipedia

  • Amikhelline — drugbox IUPAC name = 9 (2 diethylaminoethoxy) 4 hydroxy 7 methylpyrano [3,2 f] [1] benzoxol 5 one width=250 CAS number = 4439 67 2 ATC prefix = ATC suffix = ATC supplemental = PubChem = 71198 DrugBank = C=18 | H=21 | N=1 | O=5 molecular weight =… …   Wikipedia

  • brostallicin — A substance being studied in the treatment of cancer. It is a type of DNA intercalator …   English dictionary of cancer terms

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