aminolevulinic acid

aminolevulinic acid
A drug used to treat a precancerous skin condition called actinic keratosis. It is also being studied in the treatment of skin cancer and other types of cancer. When absorbed by abnormal cells and exposed to light, aminolevulinic acid becomes active and kills the cells. It is a type of photosensitizing agent.

English dictionary of cancer terms . 2015.

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  • Aminolevulinic acid — δ Aminolevulinic acid Systematic (IUPAC) name 5 amino 4 oxo pentanoic acid Clinical data Pregnancy cat.  ? …   Wikipedia

  • aminolevulinic acid — noun Any amino derivative of levulinic acid, but especially 5 aminolevulinic acid which is an intermediate in the biosynthesis of porphyrin …   Wiktionary

  • aminolevulinic acid — (ALA) ami·no·lev·u·lin·ic ac·id (ALA) (ə me″no lev″u linґik) δ aminolevulinic acid; an intermediate in the synthesis of heme, produced from succinyl CoA and glycine. Two molecules of ALA are condensed to form porphobilinogen …   Medical dictionary

  • Aminolevulinic acid dehydratase deficiency porphyria — (also known as Doss porphyria, [1] and Plumboporphyria [1]) is a cutaneous condition, disease can present during early childhood (as well as in adulthood) with acute neurologic symptoms that resemble those encountered in acute intermittent… …   Wikipedia

  • Aminolevulinic acid synthase — protein Name = aminolevulinate, delta , synthase 1 caption = width = HGNCid = 396 Symbol = ALAS1 AltSymbols = ALAS3, ALAS EntrezGene = 211 OMIM = 125290 RefSeq = NM 000688 UniProt = P13196 PDB = ECnumber = Chromosome = 3 Arm = p Band =… …   Wikipedia

  • aminolevulinic acid hydrochloride — the hydrochloride salt of aminolevulinic acid, applied topically in the treatment of nonhyperkeratotic actinic keratoses of the face and scalp. It is metabolized to protoporphyrin IX, a photosensitizer, which accumulates in the skin at the sites… …   Medical dictionary

  • D-Aminolevulinic acid — (dALA or δ ALA or 5 aminolevulinic acid) is the first compound in the porphyrin synthesis pathway, the pathway that leads to hemoglobin in mammals.In non photosynthetic eukaryotes such as animals, insects, fungi, and protozoa, as well as the α… …   Wikipedia

  • δ-aminolevulinic acid — An acid formed by δ aminolevulinate synthase from glycine and succinyl coenzyme A; a precursor of porphobilinogen, hence an important intermediate in the biosynthesis of heme. ALA levels are elevated in cases of lead poisoning. δ aminolevulinic… …   Medical dictionary

  • aminolevulinic — adjective Of or pertaining to aminolevulinic acid or its derivatives …   Wiktionary

  • α-amino-β-ketoadipic acid — An intermediate of porphobilinogen synthesis formed by δ aminolevulinic acid synthase from succinyl CoA and glycine; it rapidly decarboxylates to δ aminolevulinic acid …   Medical dictionary

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