A drug used to help reduce the risk of rejection of organ and bone marrow transplants by the body. It is also used in clinical trials to make cancer cells more sensitive to anticancer drugs.

English dictionary of cancer terms . 2015.

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  • cyclosporine — [sī΄klō spôr′ēn, sī΄kləspôr′ēn] n. a drug, produced by a fungus (Tolypocladium inflatum), that suppresses the T cells that reject foreign tissue after an organ transplant without suppressing other cells that fight infections and cancer: also… …   English World dictionary

  • Cyclosporine — Ciclosporine Cyclosporine Général Nom IUPAC [R [[R*,R* (E)]] cyclic(L alanyl D alanyl N methyl L leucyl N methyl L leucyl N methyl L valyl 3 hydroxy N,4 dimethyl L 2 amino 6 octenoyl L α amino butyryl …   Wikipédia en Français

  • cyclosporine — ciclosporine [ siklospɔrin ] n. f. VAR. cyclosporine • cyclosporine 1976; de cyclo et spore ♦ Médicament immunodépresseur utilisé pour éviter les réactions de rejet après une greffe d organe. ● ciclosporine ou cyclosporine nom féminin Médicament… …   Encyclopédie Universelle

  • cyclosporine — cyclosporin cyclosporin, cyclosporine cyclosporine . a chemical substance produced by some soil fungi, which suppresses the cellular immune response by inhibiting T cell activation, and has been used in medicine to reduce foreign tissue rejection …   The Collaborative International Dictionary of English

  • cyclosporine A — ciklosporinas A statusas T sritis chemija apibrėžtis Ciklinis peptidas, imuniteto reguliatorius. atitikmenys: angl. cyclosporine A rus. циклоспорин A …   Chemijos terminų aiškinamasis žodynas

  • cyclosporine-associated arteriopathy — a manifestation of chronic cyclosporine induced nephrotoxicity, consisting of hyaline degeneration of the tunica media and mucoid thickening of the intima of the arterioles of the peripheral vascular tree …   Medical dictionary

  • cyclosporine effect — perimyocytic fibrosis (with interstitial cellular infiltrates) occurring in transplanted hearts, due to the use of cyclosporine …   Medical dictionary

  • cyclosporine — also cyclosporin noun Etymology: International Scientific Vocabulary cycl + spor + 2 ine Date: 1976 an immunosuppressive polypeptide drug C62H111N11O12 obtained from various imperfect fungi and used especially to …   New Collegiate Dictionary

  • cyclosporine — /suy kleuh spawr een, in, spohr , sik leuh /, n. Pharm. a substance, synthesized by certain soil fungi, that suppresses the immune response by disabling helper T cells, used to minimize rejection of foreign tissue transplants. Also, cyclosporin… …   Universalium

  • cyclosporine — noun a cyclic oligopeptide, obtained from soil fungi, used as an immunosuppressive drug after an organ transplant …   Wiktionary

  • cyclosporine — A cyclic oligopeptide immunosuppressant produced by the fungus Tolypocladium inflatum Gams; used to inhibit organ transplant rejection. SYN: cyclosporin A. * * * cy·clo·spor·ine .sī klə spȯr ən, .ēn n a cyclosporin C62H111N11O …   Medical dictionary

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